New shot aims to cure hepatitis b – early trial underway
NCT ID NCT07370207
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests an experimental drug called AHB-137 in 84 adults with chronic hepatitis B who are already on antiviral therapy. The goal is to see if AHB-137 can clear the hepatitis B surface antigen and keep the virus under control, potentially leading to a functional cure. Participants will receive injections and be monitored for safety and response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AHB-137 (injection)
What this could lead to
If successful, this could point toward a functional cure for chronic hepatitis B, allowing patients to stop long-term antiviral therapy.
What could go wrong
This is an early Phase 2 trial with only 84 participants, so results may not apply broadly. The treatment may not achieve sustained response, and side effects are still being evaluated.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Asan Medical Center
NOT_YET_RECRUITINGSeoul, 05505, South Korea
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Chiayi Christian Hospital
NOT_YET_RECRUITINGChiayi City, 60002, Taiwan
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E-DA Hospital
NOT_YET_RECRUITINGKaohsiung City, 82445, Taiwan
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National Taiwan University Hospital
NOT_YET_RECRUITINGTaipei, 100, Taiwan
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National University Hospital - Singapore
NOT_YET_RECRUITINGSingapore, 119074, Singapore
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New Zealand Clinical Research
RECRUITINGGrafton, Auckland, 1010, New Zealand
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Queen Mary Hospital - PPDS
RECRUITINGHong Kong, China
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St Vincents Hospital Melbourne
RECRUITINGFitzroy, Victoria, 3065, Australia