New shot aims to cure hepatitis b – early trial underway
NCT ID NCT07370207
First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 3 times
Summary
This Phase 2 trial tests an experimental drug called AHB-137 in 84 adults with chronic hepatitis B who are already on antiviral therapy. The goal is to see if AHB-137 can clear the hepatitis B surface antigen and keep the virus under control, potentially leading to a functional cure. Participants will receive injections and be monitored for safety and response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AHB-137 (injection)
- What this could lead to
- If successful, this could point toward a functional cure for chronic hepatitis B, allowing patients to stop long-term antiviral therapy.
- What could go wrong
- This is an early Phase 2 trial with only 84 participants, so results may not apply broadly. The treatment may not achieve sustained response, and side effects are still being evaluated.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Asan Medical Center
WITHDRAWNSeoul, 05505, South Korea
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Chiayi Christian Hospital
RECRUITINGChiayi City, 60002, Taiwan
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E-DA Hospital
NOT_YET_RECRUITINGKaohsiung City, 82445, Taiwan
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Japanese Red Cross Musashino Hospital
NOT_YET_RECRUITINGMusashino, Tokyo, 180-0023, Japan
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National Center for Global Health and Medicine
NOT_YET_RECRUITINGShinjuku-Ku, Tokyo, 162-8655, Japan
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National Taiwan University Hospital
RECRUITINGTaipei, 100, Taiwan
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National University Hospital - Singapore
NOT_YET_RECRUITINGSingapore, 119074, Singapore
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New Zealand Clinical Research
RECRUITINGGrafton, Auckland, 1010, New Zealand
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Queen Mary Hospital - PPDS
RECRUITINGHong Kong, China
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St Vincents Hospital Melbourne
RECRUITINGFitzroy, Victoria, 3065, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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