Can a monthly injection halt MS before it takes hold?
NCT ID NCT05084638
First seen Mar 07, 2026 · Last updated May 05, 2026 · Updated 10 times
Summary
This study looked at whether a monthly injection of ofatumumab can stop or slow down multiple sclerosis (MS) in people who were diagnosed very early and had not yet taken any other MS medication. About 180 people with early relapsing-remitting MS received the drug for 18 months, and their results were compared to a group of healthy volunteers. The goal was to see if treatment could make the MS group look more like the healthy group in terms of brain scans, relapses, and disability progression.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arizona Neuroscience Research LLC
Phoenix, Arizona, 85032, United States
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Barrow Neurological Clinics at St Josephs Hospital and MC
Phoenix, Arizona, 85013, United States
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Caribbean Center for Clinical Research, Inc
Guaynabo, 00968, Puerto Rico
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Emerald Coast Neurology
Pensacola, Florida, 32514, United States
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Evergreen Health Multiple Sclerosis Center
Kirkland, Washington, 98034, United States
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First Choice Neurology
Boca Raton, Florida, 33486, United States
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Henry Ford Hospital
Detroit, Michigan, 48202-2689, United States
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Keck School of Medicine
Los Angeles, California, 90033, United States
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Lonestar Neurology of San Antonio
San Antonio, Texas, 78258, United States
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Lundquist Inst BioMed at Harbor
Torrance, California, 90509-2910, United States
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MD First Research
Chandler, Arizona, 85226, United States
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MedStar Health
Washington D.C., District of Columbia, 20007, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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MultiCare Neuroscience Center of Washington
Tacoma, Washington, 98405, United States
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Multiple Sclerosis Center of Excellence of OMRF
Oklahoma City, Oklahoma, 73104, United States
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Neurology Associates PA
Maitland, Florida, 32751, United States
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Neurology Diagnostics Inc
Dayton, Ohio, 45408, United States
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Neurology of Central FL Res Ctr
Altamonte Springs, Florida, 32714, United States
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Neuroscience Institute at Hackensack
Hackensack, New Jersey, 07601, United States
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Ochsner Cancer Institute
New Orleans, Louisiana, 70121, United States
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Orlando Health Clinical Trials
Orlando, Florida, 32806, United States
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Regina Berkovich MD PhD Inc
West Hollywood, California, 90048, United States
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Renown Institute for Neurosciences
Reno, Nevada, 89521, United States
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Shepherd Center
Atlanta, Georgia, 30309, United States
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Sibyl Wray MD Neurology PC
Knoxville, Tennessee, 37922, United States
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Tallahassee Neurological Clinic
Tallahassee, Florida, 32308, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107-5098, United States
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UC Health Neuroscience Ctr
Aurora, Colorado, 80045, United States
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UT Health Science Center
Houston, Texas, 77030, United States
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Univ of Texas Southwest Med Center
Dallas, Texas, 75390-9034, United States
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University Of South Florida
Tampa, Florida, 33612, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Massachusetts Medical School
Worcester, Massachusetts, 01655, United States
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University of New Mexico
Albuquerque, New Mexico, 87131-0001, United States
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Velocity Clinical Research
Raleigh, North Carolina, 27607, United States
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West Virginia University Hospital
Morgantown, West Virginia, 26506, United States
Conditions
Explore the condition pages connected to this study.