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Agility drills might sharpen aging brains and steady aging steps

NCT ID NCT05537363

Prevention Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This study tests whether agility training, which involves quick stops, direction changes, and spatial awareness, can improve movement and thinking in older adults, both those with mild cognitive impairment and those without. Researchers will compare agility training, multicomponent exercise, and health education over 8 weeks, then track participants for up to a year. They will measure agility, cognitive function, fall history, and brain activity during tasks. The goal is to see if such training can reduce fall risk and support healthy aging.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Agility training and multicomponent exercise programs, compared with health education
What this could lead to
If effective, agility training could offer a practical way to improve physical and mental function and reduce falls in older adults, including those with mild cognitive impairment.
What could go wrong
This is an early-stage study with a modest number of participants, so results may not apply broadly. Training requires regular attendance, and benefits may fade after the program ends.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

83 people

The number who actually took part.

Started

Sep 2022

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 100 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Part 1: Inclusion Criteria: 1. has a score of ≥ 24 on the Mini-Mental State Examination (MMSE) 2. able to walk independently for more than 30 meters without assistive aids 3. able to follow orders Exclusion Criteria: 1. poorly-controlled or unstable systematic disease 2. has a history of central nervous system disease 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain 4. subjects with achromatopsia Part 2: Inclusion Criteria: 1. older than 65 years old 2. score of Mini-Mental State Examination (MMSE) ≥ 24 and score of Montreal Cognitive Assessment (MoCA) ≤ 26 3. able to walk independently for more than 30 meters without assistive aids 4. able to follow orders Exclusion Criteria: 1. poorly controlled or unstable systematic disease 2. has a history of central nervous system disease 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain 4. has other medical conditions for which exercise is contraindicated 5. subjects with achromatopsia Part 3: Inclusion Criteria: 1. older than 65 years old 2. score of Mini-Mental State Examination (MMSE) ≥ 24 3. able to walk independently for more than 30 meters without assistive aids 4. able to follow orders Exclusion Criteria: 1. poorly controlled or unstable systematic disease 2. has a history of central nervous system disease 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain 4. has other medical conditions for which exercise is contraindicated 5. subjects with achromatopsia

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Elderly adults Healthy Mild cognitive impairment

Contacts and locations

Locations

  • National Taiwan University

    Taipei, Taiwan

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Other studies related to the condition(s) this trial covers.