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New Bone-Boosting drug shows promise for osteoporosis

NCT ID NCT06577935

Ongoing Disease control Sponsor: Angitia Biopharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests an experimental drug called AGA2118 in postmenopausal women aged 55 to 80 who have low bone density but no history of fractures. The goal is to see if the drug can safely increase bone mineral density over 12 months compared to a placebo. About 379 women will participate in this double-blind, dose-finding trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AGA2118
What this could lead to
If successful, this could lead to a new treatment option that helps strengthen bones and reduce fracture risk in postmenopausal women with osteoporosis.
What could go wrong
This is an early Phase 2 dose-finding study, so it is not yet proven to work. The results may not lead to a final approved treatment, and side effects are still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoporosis postmenopausal osteoporosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTMENOPAUSAL OSTEOPOROSIS

Contacts and locations

Locations

  • Altoona Center for Clinical Research

    Duncansville, Pennsylvania, 16635, United States

  • CE "Hospital #1" of Zhytomyr City Council

    Kyiv, Ukraine, Ukraine

  • CIDIIM

    Córdoba, Argentina

  • Center for Advanced Research & Education

    Gainesville, Georgia, 30501, United States

  • Centro Médico Dra Laura Maffei e Investigación Cliínica Aplicada

    Buenos Aires, Argentina, Argentina

  • Centro de Investigaciones Medicas Mar del Plata CIM

    Mar del Plata, Argentina

  • Consultorio de Investigacion Clinica EMO SRL

    Buenos Aires, Argentina, Argentina

  • Futuremeds Gdynia

    Gdynia, 81-384, Poland

  • Futuremeds Lodz

    Lodz, 91-363, Poland

  • Futuremeds Targowek

    Warsaw, 03-291, Poland

  • Futuremeds Warszawa Centrum

    Warsaw, 00-215, Poland

  • Futuremeds Wroclaw

    Wroclaw, 53-673, Poland

  • IDIM

    Buenos Aires, Argentina, Argentina

  • Instituto Médico Strusberg

    Córdoba, Argentina, Argentina

  • Investigaciones Reumatologicas y Osteologicas SRL

    Buenos Aires, Argentina, Argentina

  • Krakowskie Centrum Medyczne

    Krakow, 31-501, Poland

  • Mautalen - Salud e Investigacion (Expertia S.A.)

    Buenos Aires, Argentina, Argentina

  • Medical Center Universal Clinic "Oberig" of "Kapytal" LCC

    Kyiv, Ukraine, Ukraine

  • NM Clinical Research & Osteoporosis Center, Inc.

    Albuquerque, New Mexico, 87160, United States

  • PSSE Medical Centre Pulse

    Vinnytsia, Ukraine, Ukraine

  • Puget Sound Osteoporosis Center

    Burien, Washington, 98166, United States

  • Stat Research

    Buenos Aires, Argentina, Argentina

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

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