Hidden hormone danger: common adrenal tumors may raise heart risk

NCT ID NCT04917757

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at over 3,600 people with adrenal tumors found by chance. Researchers want to see if mild cortisol excess from these tumors is linked to higher risk of death or heart problems like heart attack and stroke. Participants had a simple overnight dexamethasone test to measure cortisol levels and were followed for at least three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better identify which adrenal tumor patients need treatment to prevent heart issues or early death.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma Adrenal incidentaloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Würzburg

    Würzburg, 97080, Germany

  • University Turin

    Turin, Italy

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