Hidden hormone danger: common adrenal tumors may raise heart risk

NCT ID NCT04917757

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at over 3,600 people with adrenal tumors found by chance. Researchers want to see if mild cortisol excess from these tumors is linked to higher risk of death or heart problems like heart attack and stroke. Participants had a simple overnight dexamethasone test to measure cortisol levels and were followed for at least three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better identify which adrenal tumor patients need treatment to prevent heart issues or early death.

What could go wrong

This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma Adrenal incidentaloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Würzburg

    Würzburg, 97080, Germany

  • University Turin

    Turin, Italy