Can a blood protein predict better diabetes treatment?
NCT ID NCT07539584
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study in 130 adults with type 2 diabetes and fatty liver disease tested whether a blood marker called adiponectin can predict how well certain diabetes drugs reduce liver fat. Participants received either an SGLT2 inhibitor, a GLP-1 receptor agonist, or both for six months. The goal was to see if changes in adiponectin levels matched improvements in liver health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SGLT2 inhibitors (dapagliflozin or empagliflozin) and GLP-1 receptor agonists
- What this could lead to
- If successful, this could help doctors predict which diabetes medications best reduce liver fat in patients with fatty liver disease.
- What could go wrong
- This is a small, completed study focused on a biomarker, not a treatment outcome. Results may not lead to new therapies or apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Moscow Regional Research and Clinical Institute
Moscow, 129110, Russia
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