New drug targets arginine to fight liver cancer in phase 3 trial

NCT ID NCT05317819

First seen Jan 05, 2026 · Last updated May 10, 2026 · Updated 23 times

Summary

This study tests a drug called ADI-PEG 20 against a placebo in 300 people with advanced liver cancer that cannot be removed by surgery and who have high levels of the amino acid arginine in their blood. The goal is to see if the drug helps people live longer. Participants must have had at least one prior cancer treatment or be unable to get standard therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bach Mai Hospital

    NOT_YET_RECRUITING

    Hanoi, 100000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Chia-Yi (CGMF-CY)

    RECRUITING

    Chiayi City, 613, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Kaohsiung(CGMF-KS)

    RECRUITING

    Kaohsiung City, 833, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Linkou (CGMF-LK)

    RECRUITING

    Taoyuan, 333, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changhua Christian Hospital (CCH)

    RECRUITING

    Changhua, 500, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chi Mei Hospital, Liouying (CMMC-LY)

    RECRUITING

    Tainan, 736, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chi Mei Medical Center (CMMC-YK)

    RECRUITING

    Tainan, 710, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ditmanson Medical Foundation Chiayi Christian Hospital (CYCH)

    RECRUITING

    Chiayi City, 600, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hue Central Hospital

    NOT_YET_RECRUITING

    Huế, 49000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • K Hospital

    NOT_YET_RECRUITING

    Hà Nội, 100000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH)

    RECRUITING

    Kaohsiung City, 807, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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