New drug targets liver cancer by starving tumors of arginine

NCT ID NCT05317819

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called ADI-PEG 20 against a placebo in 300 people with advanced liver cancer that cannot be removed by surgery. Only people with high levels of the amino acid arginine in their blood can join. The goal is to see if the drug helps them live longer by breaking down arginine, which some cancers need to grow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bach Mai Hospital

    NOT_YET_RECRUITING

    Hanoi, 100000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Chia-Yi (CGMF-CY)

    RECRUITING

    Chiayi City, 613, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Kaohsiung(CGMF-KS)

    RECRUITING

    Kaohsiung City, 833, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chang Gung Medical Foundation-Linkou (CGMF-LK)

    RECRUITING

    Taoyuan, 333, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changhua Christian Hospital (CCH)

    RECRUITING

    Changhua, 500, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chi Mei Hospital, Liouying (CMMC-LY)

    RECRUITING

    Tainan, 736, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chi Mei Medical Center (CMMC-YK)

    RECRUITING

    Tainan, 710, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ditmanson Medical Foundation Chiayi Christian Hospital (CYCH)

    RECRUITING

    Chiayi City, 600, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hue Central Hospital

    NOT_YET_RECRUITING

    Huế, 49000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • K Hospital

    NOT_YET_RECRUITING

    Hà Nội, 100000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH)

    RECRUITING

    Kaohsiung City, 807, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••