Brain study targets motivation loss in depressed teens

NCT ID NCT05487885

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at anhedonia, a symptom of depression where people lose interest or pleasure in activities. Researchers used brain scans, blood tests, and questionnaires to understand this symptom in 123 young people. Some participants also tried treatments like brain stimulation or ketamine to see if they could improve motivation and enjoyment.

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Conditions

The condition(s) this trial relates to.

Anhedonia Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Loeffler Building

    Pittsburgh, Pennsylvania, 15213, United States

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