New chemo combo aims to wipe out aggressive breast cancer before surgery

NCT ID NCT04335669

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 25 times

Summary

This study tests whether adding the drug capecitabine to standard chemotherapy before surgery can completely eliminate early triple-negative breast cancer. About 325 adults with node-positive or larger tumors are participating. The main goal is to see if the combination leads to no cancer remaining at the time of surgery.

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Contacts and locations

Locations

  • Aalborg Universitetshospita

    Aalborg, 9000, Denmark

  • Academical Hospital, Department of Oncology

    Uppsala, 753 09, Sweden

  • Capio S:t Göran Hospital, Department of Oncology

    Stockholm, 112 19, Sweden

  • Centralsjukhuset i Kristianstad

    Kristianstad, Skåne County, 291 85, Sweden

  • Gävle hospital, Department of Oncology

    Gävle, 803 24, Sweden

  • Halmstad Hospital, Department of Surgery

    Halmstad, 302 33, Sweden

  • Karlstad Hospital

    Karlstad, 652 30, Sweden

  • Nordsjællands Hospital

    Hillerød, 3400, Denmark

  • Norrland University Hospital, Department of Oncology

    Umeå, 907 37, Sweden

  • Regionsjælland Næstved Sygehus

    Næstved, 4700, Denmark

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • Ryhov Hospital

    Jönköping, 551 85, Sweden

  • Sahlgrenska University Hospital, Department of Oncology

    Gothenburg, 413 46, Sweden

  • Skåne University Hospital, Department of Oncology

    Malmö, 20501, Sweden

  • Sundsvall hospital

    Sundsvall, 851 86, Sweden

  • Sydvestjysk Sygehus

    Esbjerg, 6700, Denmark

  • Södersjukhuset, Department of Oncology

    Stockholm, 118 61, Sweden

  • Södra Älvsborgs Hospital

    Borås, 501 82, Sweden

  • Sønderborg sygehus

    Sønderborg, 6300, Denmark

  • Vejle Hospital

    Vejle, Region Syd, 7100, Denmark

  • Vejle syghus

    Vejle, 7100, Denmark

  • Västmanlands Hopsital Västerås

    Västerås, 721 89, Sweden

  • Växjö Hospital, Department of Oncology

    Vaxjo, 352 34, Sweden

  • Örebro University Hospital, Department of Oncology

    Örebro, 701 85, Sweden

Conditions

Explore the condition pages connected to this study.