A lockbox for pain pills: could a password-protected dispenser curb opioid misuse after cancer surgery?

NCT ID NCT05585788

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests a device called Addinex that stores opioid pills and releases them only with a unique passcode. Adults having cancer-related surgery who expect to need opioids for pain will use the device instead of a standard pill bottle. Researchers will measure how many unused pills are returned and whether patients request fewer refills. The goal is to see if the device helps prevent leftover opioids from being misused.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Addinex Device (ADX-27)
What this could lead to
If effective, this device could offer a safer way to manage pain after cancer surgery, reducing leftover opioids and the risk of misuse.
What could go wrong
This is a small, early-stage study focused on device usability and disposal rates, not on pain control or clinical outcomes. The device may not change how patients use or dispose of opioids in real-world settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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