AI-Powered daily radiation adjustments aim to improve anal cancer treatment
NCT ID NCT05838391
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether using artificial intelligence to adjust radiation plans daily can better target tumors while sparing healthy organs in people with locally advanced anal cancer. Twenty participants will receive standard radiation over six weeks, but each day's plan is adapted based on that day's anatomy. The study primarily looks at whether this approach is practical and how long it takes, while also tracking side effects and tumor response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Adaptive radiotherapy (AI-guided daily radiation plan adjustments)
- What this could lead to
- If successful, this approach could make radiation therapy more precise, potentially reducing side effects and improving tumor control for anal cancer patients.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply broadly. The main focus is on feasibility, not yet on effectiveness, and daily adaptive planning may increase treatment time or complexity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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