AI-Powered daily radiation adjustments aim to improve anal cancer treatment

NCT ID NCT05838391

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether using artificial intelligence to adjust radiation plans daily can better target tumors while sparing healthy organs in people with locally advanced anal cancer. Twenty participants will receive standard radiation over six weeks, but each day's plan is adapted based on that day's anatomy. The study primarily looks at whether this approach is practical and how long it takes, while also tracking side effects and tumor response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adaptive radiotherapy (AI-guided daily radiation plan adjustments)

What this could lead to

If successful, this approach could make radiation therapy more precise, potentially reducing side effects and improving tumor control for anal cancer patients.

What could go wrong

This is a very small pilot study with only 20 participants, so results may not apply broadly. The main focus is on feasibility, not yet on effectiveness, and daily adaptive planning may increase treatment time or complexity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma anus neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Email: •••••@•••••

    Contact

    Contact