Personalized muscle training may ease leg pain from blocked arteries

NCT ID NCT04800276

Recruiting now Symptom relief Sponsor: Centre Hospitalier le Mans Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether a personalized exercise program—focusing on the specific leg muscles affected by blocked arteries—can help people with peripheral arterial disease walk longer distances without pain. Participants are randomly assigned to either a tailored muscle-strengthening program or a general strengthening program. The goal is to see if targeting the exact areas of poor blood flow leads to greater improvements in walking ability and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: adapted physical activity (muscle strengthening)
What this could lead to: If it works, this approach could offer a more effective exercise program to help people with peripheral arterial disease walk farther and feel better.
What could go wrong: This is a small, early-stage study with 70 participants, so results may not apply to everyone. Exercise programs require ongoing commitment, and benefits may vary.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE

Contacts and locations

Locations

Centre Hospitalier Du Mans
RECRUITING

Le Mans, 72000, France

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