Acupuncture needles take on radiation dry mouth in major trial

NCT ID NCT01266044

Ongoing Prevention Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 3 trial tests whether acupuncture can prevent dry mouth (xerostomia) in 435 head and neck cancer patients receiving radiation. Participants are split into two different acupuncture groups or a standard care group. The study compares which approach better reduces dry mouth symptoms and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: acupuncture
What this could lead to: If it works, this could offer a drug-free way to prevent dry mouth in head and neck cancer patients undergoing radiation, improving their quality of life.
What could go wrong: This is a Phase 3 trial, but results are not yet reported. Acupuncture may not be more effective than standard care, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms oropharynx cancer Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER

Contacts and locations

Locations

Fudan University Cancer Hospital

Shanghai, China
University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

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