New radioactive drug targets Hard-to-Treat prostate cancer
NCT ID NCT07414940
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a new injectable radioactive drug, Actinium-225 rhPSMA-10.1, in 60 men with advanced prostate cancer that has spread and stopped responding to other treatments. The drug is designed to attach to prostate cancer cells and destroy them with radiation. The study aims to find safe doses and see if the drug can shrink tumors or lower PSA levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Actinium-225 rhPSMA-10.1 (a radioactive drug injected into the body to target and destroy prostate cancer cells)
- What this could lead to
- If it works, this could offer a new treatment option for men with advanced prostate cancer who have run out of effective therapies.
- What could go wrong
- This is an early-phase trial with only 60 participants, so the drug may not prove safe or effective. Radioactive drugs can cause side effects like damage to healthy tissues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University College London Hospital
RECRUITINGLondon, WC1E 6BT, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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