Can a gel tame eye inflammation? new trial tests ACTH for uveitis
NCT ID NCT02931175
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested ACTH gel, given as a shot under the skin, in 28 people with non-infectious uveitis (eye inflammation not caused by an infection). The goal was to see if it is safe and can help control inflammation. Participants received one of two doses, and researchers tracked side effects and changes in eye haze over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ACTH gel (corticotropin)
What this could lead to
If successful, this could provide a new treatment option for controlling inflammation in non-infectious uveitis, potentially reducing reliance on steroids.
What could go wrong
This is a small, early-phase (Phase 2) study with only 28 participants, so results may not apply to all patients. The treatment may cause side effects and may not work better than existing therapies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Metropolitan Eye Research and surgery Institute
Waltham, Massachusetts, 02451, United States
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Retina Centers Professional Corporation - RCPC
Cleveland, Ohio, 44139, United States
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Retina Consultants of Houston
Bellaire, Texas, 77401, United States
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Retina Vitreous Associates, Medical Group
Los Angeles, California, 90017, United States
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Stanford University
Palo Alto, California, 94303, United States
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TExas Retina Associates
Dallas, Texas, 75231, United States
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Texas Retina Assiciates
Dallas, Texas, 75231, United States