Mind over marrow: ACT therapy aims to boost transplant recovery

NCT ID NCT04423939

Completed Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a type of talk therapy called Acceptance and Commitment Therapy (ACT) for people undergoing stem cell transplants. The goal was to help patients cope with the physical and emotional stress of the procedure, improve their physical function, and possibly shorten hospital stays. Thirty-three patients and their caregivers participated in therapy sessions and used activity trackers over three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Acceptance and Commitment Therapy (ACT)
What this could lead to: If successful, this therapy could help stem cell transplant patients better manage stress and physical decline, potentially improving recovery and reducing hospital stays.
What could go wrong: This is a small, early-stage study with only 33 participants and no control group, so results may not apply broadly. The therapy requires significant time and commitment from both patients and caregivers.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMATOPOIETIC STEAM CELL TRANSPLANTATION (HCT)

Contacts and locations

Locations

Lauren Hill

Raleigh, North Carolina, 27608, United States

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