Knee fluid drain or blood injection may curb arthritis after ACL tear
NCT ID NCT07142369
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two procedures done before ACL surgery: draining excess knee joint fluid (arthrocentesis) or injecting platelet-rich plasma (PRP) from the patient's own blood. The goal is to see if either reduces inflammatory chemicals linked to cartilage damage. About 99 adults aged 18-50 with a recent ACL tear and swelling will take part. The results could help prevent long-term arthritis after knee injuries.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Platelet-rich plasma (PRP)
What this could lead to
If it works, this could point toward a way to reduce joint inflammation and cartilage breakdown after an ACL tear, potentially lowering the risk of post-traumatic arthritis.
What could go wrong
This is a small, early-stage study (99 people) testing a procedure, not a drug. The benefits may be modest or not show up at all, and PRP injections carry a small risk of infection or pain at the injection site.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Rush University Medical Center
Chicago, Illinois, 60612, United States