Why some knees freeze after ACL surgery: scientists probe muscle inhibition

NCT ID NCT07659561

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why some people have trouble activating their quadriceps (front thigh muscle) after ACL surgery, a condition called arthrogenic motor inhibition (AMI). Researchers will use surface electrodes to measure muscle activity in both legs of 40 patients who had ACL surgery at least 3 weeks ago. By comparing those with and without AMI, they hope to better understand this barrier to recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better diagnose and treat muscle inhibition after ACL surgery, potentially improving rehabilitation outcomes.
What could go wrong
This is a small, early-stage observational study with only 40 participants. It measures electrical activity, not clinical recovery, so results may not directly change treatment.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Privé Jean Mermoz

    Lyon, 69008, France

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