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Knee surgery showdown: patella, hamstring, or quadriceps tendon?

NCT ID NCT03073083

Disease control Sponsor: Orthopedisch Centrum Oost Nederland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared three types of tendon grafts used in ACL reconstruction surgery: patella, hamstring, and quadriceps. Researchers wanted to see which one leads to fewer failures and better knee function two years after surgery. The trial included 439 active patients with a torn ACL, but it ended early, so the results are exploratory and not definitive.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical procedure using either patella, hamstring, or quadriceps tendon graft
What this could lead to
If successful, this could help doctors choose the best graft for ACL surgery, improving knee stability and reducing failure rates.
What could go wrong
The trial ended early, so results are less reliable. Graft choice may not significantly affect outcomes, and individual healing varies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 439 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2017

Expected to finish

Dec 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients active in sports, Tegner =/\>5 * Primary ACL rupture, evident from anamnesis (acute trauma, snapping sensation, swelling within several hours, feeling of instability), physical examination (positive Lachman test, anterior drawertest and/or pivot shift test), radiograph and MRl * Willing to comply to the suggested (nationwide standard) rehabilitation protocol, supen/ised by a NFVS registerd sport-physical therapist * \<6 months between initial trauma and surgery Exclusion Criteria: * History of knee surgery on the same side * History of tendon removal on the same side * Accompanying ligament injury ofthe knee, evident from anamnesis, physical examination, radiograph and MRl, defined as an ACL rupture in combination with a posterior cruciate ligament or collateral ligament injury, * Peroperative discovery of cartilage damage; larger than 2cm2 and more than 50% depth * Peroperative discovery of meniscus injury witch requires a meniscectomy of more than 20% or meniscus sutures * Osteoarthritis of Kellgren and Lawrence grade 2 or more, as evident from the radiograph * Severe malalignment of the leg * Tendency to form excessive scar tissue, such as arthrofibrosis * Muscular, neurological or vascular anomalies that influence healingtime or rehabilitation * Infection * Known hypersensitivity to any of the used materials * Long term relevant medication use such as prednisolone or cytostatics * Pregnancy at the time of inclusion or surgery * Known osteoporosis

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament injuries

Contacts and locations

Locations

  • Martini Hospital Groningen

    Groningen, 9728 NT, Netherlands

  • OCON

    Hengelo, Netherlands

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