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Virus cocktail targets tough lung bugs in cystic fibrosis trial

NCT ID NCT07275905

Recruiting now Disease control Sponsor: Ghady Haidar Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This early-stage trial tests a new treatment called AchromoPhage, a mix of four viruses that specifically kill Achromobacter bacteria, in 12 adults with cystic fibrosis and chronic lung infections. Participants will receive the treatment by inhalation, IV, or both over three weeks. The main goal is to see if it is safe and tolerable, while also checking for any changes in lung function and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AchromoPhage (a mixture of four naturally occurring viruses called bacteriophages that target Achromobacter bacteria)
What this could lead to
If safe and effective, this could lead to a new way to treat stubborn lung infections in people with cystic fibrosis, potentially improving lung function and quality of life.
What could go wrong
This is a very early Phase 1 trial with only 12 participants, so it is primarily testing safety, not effectiveness. The treatment may cause side effects or not work as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACHROMOBACTER INFECTION CYSTIC FIBROSIS (CF)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California San Diego (UCSD)

    NOT_YET_RECRUITING

    San Diego, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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