Tylenol tested as a secret weapon against MS walking fatigue

NCT ID NCT07440446

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether acetaminophen (Tylenol) can reduce walking fatigue in people with multiple sclerosis. Twenty participants will take either the drug or a placebo, then walk on a treadmill until they get tired. A week later, they repeat the test with the opposite pill. The goal is to see if lowering body temperature helps them walk longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acetaminophen

What this could lead to

If it works, this could point toward a simple, low-cost way to help people with MS walk longer before getting tired.

What could go wrong

This is a very small, early study with only 20 people. The effect may be small or not real, and results may not apply to everyone with MS.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fatigue multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hunter College Physical Therapy department

    New York, New York, 10065, United States