New implant could make dialysis easier for kidney patients

NCT ID NCT05425056

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 16 times

Summary

This study tested a special collagen implant that slowly releases a drug called sirolimus. It was placed around a new blood vessel connection (fistula) during surgery in 136 people aged 65+ with kidney failure on dialysis. The goal was to see if the implant helps the fistula mature faster and work better for dialysis, reducing complications.

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Contacts and locations

Locations

  • American Access Care of Miami

    Miami, Florida, 33156, United States

  • Arteries & Veins

    El Paso, Texas, 79912, United States

  • Atrium Health

    Charlotte, North Carolina, 28204, United States

  • Augusta University

    Augusta, Georgia, 30912, United States

  • Barts Health NHS Trust of Royal London Hospital

    London, United Kingdom

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • Houston Methodist

    Sugar Land, Texas, 77479, United States

  • James Eric Gardner, MD PC

    Memphis, Tennessee, 38115, United States

  • Lundquist Institute for Biomedical Innovation

    Torrance, California, 90502, United States

  • MedStar Cardiovascular Research Network at MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • NHS Greater Glasgow and Clyde

    Glasgow, United Kingdom

  • Sentara Norfolk General Hospital/Sentara Health Research Center

    Norfolk, Virginia, 23507, United States

  • St George's University Hospitals NHS Foundation Trust

    London, United Kingdom

  • St Helier Hospital

    Carshalton, SM5 1AA, United Kingdom

  • Surgical Specialists of Charlotte

    Charlotte, North Carolina, 28207, United States

  • The Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • The Regional Medical Center/Dialysis Access Institute

    Orangeburg, South Carolina, 29118, United States

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, United Kingdom

  • University of Louisville

    Louisville, Kentucky, 40202, United States

  • Veterans Affairs San Diego Health Center

    San Diego, California, 92161, United States

Conditions

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