Radiation combo aims to fight cancer without drugs – but study never started

NCT ID NCT05578274

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study planned to test whether adding low-dose radiation to standard high-dose radiation could trigger an 'abscopal effect' – where untreated tumors also shrink. It was designed for adults with metastatic solid tumors. However, the study was withdrawn before any patients were enrolled, so no conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy (SBRT and LDRT)
What this could lead to
If it had worked, this could point toward a way to trigger the immune system to attack untreated tumors using only radiation, avoiding expensive immunotherapy.
What could go wrong
The study was withdrawn before enrolling any participants, so no results are available. The approach is still experimental and may not work in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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