Glow-in-the-Dark dye could help surgeons spot hidden lung cancer

NCT ID NCT07499674

Recruiting now Diagnosis Sponsor: Vergent Bioscience, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 3 trial tests a fluorescent dye called abenacianine that makes lung cancer cells glow under a special camera during surgery. About 132 people having lung cancer surgery will receive the dye. The goal is to see if the dye helps surgeons find tumors that are hard to see with the naked eye or standard scans. The study compares results from the dye camera to standard surgical techniques.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: abenacianine (VGT-309)
What this could lead to: If successful, this could give surgeons a real-time tool to spot hidden lung cancer during surgery, potentially reducing the chance of leaving cancer behind.
What could go wrong: This is a Phase 3 trial, but it's still experimental. The dye may cause false positives (normal tissue lighting up) or fail to find all tumors. Side effects from the dye are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER LUNG METASTASES

Contacts and locations

Locations

City of Hope National Medical Center
RECRUITING

Duarte, California, 91010, United States
Hoag Memorial Hospital Presbyterian
NOT_YET_RECRUITING

Newport Beach, California, 92663, United States
Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Orlando Health Cancer Center
RECRUITING

Orlando, Florida, 32806, United States
St. Vincent's Hospital
NOT_YET_RECRUITING

Fitzroy, Victoria, 3065, Australia
University of Colorado Hospital
RECRUITING

Aurora, Colorado, 80045, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Texas, MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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