Glow-in-the-Dark dye could help surgeons spot hidden lung cancer
NCT ID NCT07499674
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This Phase 3 trial tests a fluorescent dye called abenacianine that makes lung cancer cells glow under a special camera during surgery. About 132 people having lung cancer surgery will receive the dye. The goal is to see if the dye helps surgeons find tumors that are hard to see with the naked eye or standard scans. The study compares results from the dye camera to standard surgical techniques.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
abenacianine (VGT-309)
What this could lead to
If successful, this could give surgeons a real-time tool to spot hidden lung cancer during surgery, potentially reducing the chance of leaving cancer behind.
What could go wrong
This is a Phase 3 trial, but it's still experimental. The dye may cause false positives (normal tissue lighting up) or fail to find all tumors. Side effects from the dye are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope National Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact
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Hoag Memorial Hospital Presbyterian
NOT_YET_RECRUITINGNewport Beach, California, 92663, United States
Contact
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Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact
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Orlando Health Cancer Center
RECRUITINGOrlando, Florida, 32806, United States
Contact
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St. Vincent's Hospital
NOT_YET_RECRUITINGFitzroy, Victoria, 3065, Australia
Contact Email: •••••@•••••
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University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
Contact
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact
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University of Texas, MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact