Two-Drug cocktail shows promise for tough cancers

NCT ID NCT02779751

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether combining two drugs, abemaciclib and pembrolizumab, is safe and effective for people with advanced non-small cell lung cancer or a certain type of breast cancer. About 100 participants with stage IV disease will receive the combination. The goal is to see if the drugs work together to shrink tumors or slow cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire Sart Tilman

    Liège, 4000, Belgium

  • Centre Oscar Lambret

    Lille, Hauts-de-France, 59020, France

  • Chi Mei Hospital - Liouying Branch

    Tainan, 73657, Taiwan

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Ege Universitesi Hastanesi

    Izmir, 35100, Turkey (Türkiye)

  • Highlands Oncology Group - Duplicate 2

    Springdale, Arkansas, 72762, United States

  • Hopital Larrey

    Toulouse, 31059, France

  • Hospital Madrid Norte Sanchinarro

    Madrid, 28050, Spain

  • Hospital Nuestra Senora de Sonsoles

    Ávila, 05004, Spain

  • Hospital San Pedro de Alcantara

    Cáceres, 10003, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hôpital Arnaud de Villeneuve - CHU Montpellier

    Montpellier, Hérault, 34090, France

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy

  • Istanbul Universitesi-Cerrahpasa Cerrahpasa Tip Fakultesi Yerleskesi

    Istanbul, 34098, Turkey (Türkiye)

  • Istituto Scientifico Romagnolo - Studio e la Cura dei Tumori

    Meldola, Forli, 47014, Italy

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Karmanos Cancer Institute

    Farmington Hills, Michigan, 48334, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Taiwan University Hospital

    Taipei, 10048, Taiwan

  • Taipei Medical University- Shuang Ho Hospital

    New Taipei City, 235, Taiwan

  • Tri-Service General Hospital

    Neihu Taipei, 114, Taiwan

  • Univ of California San Francisco

    San Francisco, California, 94158, United States

  • Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg

    Leuven, 3000, Belgium

  • University of Colorado School of Medicine

    Aurora, Colorado, 80045, United States