New 24-Hour infusion shows promise for advanced Parkinson's

NCT ID NCT04379050

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing the long-term safety of ABBV-951, a drug given as a continuous 24-hour infusion under the skin for people with advanced Parkinson's disease. About 130 adults who completed an earlier study will continue receiving the treatment. Researchers will monitor side effects, infusion site reactions, and changes in symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABBV-951 (foscarbidopa/foslevodopa)

What this could lead to

If successful, this could provide a new, continuous treatment option to better control motor symptoms in advanced Parkinson's disease.

What could go wrong

This is an open-label extension with no placebo group, so results may be less reliable. Side effects like infusion site reactions, hallucinations, and weight loss are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE (PD)

Contacts and locations

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Locations

Aarhus Universitetshospital - Skejby /ID# 215392

Aarhus, Central Jutland, 8200, Denmark
Academician I.P. Pavlov First St. Petersburg State Medical University /ID# 218869

Saint Petersburg, Sankt-Peterburg, 197101, Russia
Azienda Ospedale-Universita Padova /ID# 215421

Padova, 35128, Italy
Banner Sun Health Research Institute /ID# 215579

Sun City, Arizona, 85351, United States
Baylor College of Medicine /ID# 215401

Houston, Texas, 77030, United States
Bispebjerg and Frederiksberg Hospital /ID# 215391

Copenhagen NV, Capital Region, 2400, Denmark
Booth Gardner Parkinson's Care Center /ID# 215535

Kirkland, Washington, 98034-3029, United States
Central Texas Neurology Consul /ID# 217013

Round Rock, Texas, 78681, United States
City Clinical Hospital #40 /ID# 218870

Sestroretsk, Sankt-Peterburg, 197706, Russia
Clinique Neuro Levis /ID# 215371

Lévis, Quebec, G6W 0M5, Canada
Complejo Hospitalario Universitario A Coruña /ID# 215426

A Coruña, A Coruna, 15006, Spain
Concord Repatriation General Hospital /ID# 215943

Concord, New South Wales, 2139, Australia
Dartmouth-Hitchcock Medical Center /ID# 216834

Lebanon, New Hampshire, 03756, United States
Derriford Hospital and the Royal Eye Infirmary /ID# 217390

Plymouth, Devon, PL6 8DH, United Kingdom
Duplicate_Algemeen Ziekenhuis Sint-Jan Brugge /ID# 215686

Bruges, West-Vlaanderen, 8000, Belgium
Duplicate_Groupe Sante CHC - Clinique du MontLegia /ID# 215685

Liège, 4000, Belgium
Duplicate_Osaka University Hospital /ID# 217415

Suita-shi, Osaka, 565-0871, Japan
Duplicate_Royal Adelaide Hospital /ID# 215940

Adelaide, South Australia, 5000, Australia
Hospital General Universitario de Elche /ID# 215425

Elche, Alicante, 03203, Spain
Hospital Santa Creu i Sant Pau /ID# 215429

Barcelona, 08041, Spain
Hospital Universitari de Bellvitge /ID# 215427

L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Hospital Universitario Virgen de las Nieves /ID# 215431

Granada, 18014, Spain
Hospital Universitario Virgen del Rocio /ID# 215428

Seville, 41013, Spain
IRCCS Centro Neurolesi Bonino Pulejo /ID# 215422

Messina, 98124, Italy
Indiana Clinical Research Cent /ID# 216490

Indianapolis, Indiana, 46202, United States
Inland Northwest Research /ID# 215533

Spokane, Washington, 99202-1342, United States
Karolinska Universitetssjukhuset - Huddinge /ID# 215386

Huddinge, Stockholm County, 141 57, Sweden
Kings College Hospital NHS Foundation Trust /ID# 217388

London, Greater London, SE5 9RS, United Kingdom
Kliniken Beelitz GmbH /ID# 215403

Beelitz-Heilstätten, 14547, Germany
Legacy Medical Group - Neurology /ID# 215536

Portland, Oregon, 97232-2003, United States
M3 Wake Research - Raleigh /ID# 215596

Raleigh, North Carolina, 27612-8106, United States
NHS Tayside /ID# 217389

Dundee, Scotland, DD2 1UB, United Kingdom
National Center of Neurology and Psychiatry /ID# 218763

Kodaira-shi, Tokyo, 187-8551, Japan
National Hospital Organization Asahikawa Medical Center /ID# 218762

Asahikawa-shi, Hokkaido, 070-8644, Japan
Odense University Hospital /ID# 215390

Odense, Region Syddanmark, 5000, Denmark
Parkinson's Disease and Movement Disorders Center of Boca Raton /ID# 215412

Boca Raton, Florida, 33486, United States
Perron Institute /ID# 215944

Nedlands, Western Australia, 6009, Australia
Sahlgrenska Universitetssjukhuset /ID# 215387

Gothenburg, Västra Götaland County, 413 46, Sweden
Skane University Hospital Lund /ID# 215385

Lund, Skåne County, 224 84, Sweden
St. Antonius Ziekenhuis, Locatie Utrecht /ID# 215396

Utrecht, 3543 AZ, Netherlands
The Alfred Hospital /ID# 215942

Melbourne, Victoria, 3004, Australia
Univ Kansas Med Ctr /ID# 215624

Kansas City, Kansas, 66160, United States
Univ Texas HSC San Antonio /ID# 215400

San Antonio, Texas, 78229-3901, United States
Universitaetsklinikum Ulm /ID# 215405

Ulm, Baden-Wurttemberg, 89081, Germany
Universitair Ziekenhuis Leuven /ID# 215684

Leuven, Vlaams-Brabant, 3000, Belgium
University of Alabama at Birmingham - Main /ID# 215597

Birmingham, Alabama, 35233, United States
University of Calgary /ID# 215369

Calgary, Alberta, T2N 4Z6, Canada
University of Colorado Hospital /ID# 215625

Aurora, Colorado, 80045, United States
Washington University-School of Medicine /ID# 215472

St Louis, Missouri, 63110, United States
Westmead Hospital /ID# 215941

Westmead, New South Wales, 2145, Australia
curiositas ad sanum /ID# 215404

Haag i.OB, Bavaria, 83527, Germany