New Parkinson's pump shows promise in Real-World test

NCT ID NCT06107426

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 427 adults with advanced Parkinson's disease who are receiving ABBV-951, a continuous infusion under the skin. Researchers want to see how well it controls symptoms like tremors and stiffness over three years in everyday medical practice. Participants attend regular check-ups and fill out questionnaires to track their progress.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ABBV-951 (foslevodopa/foscarbidopa) given as a continuous infusion under the skin
What this could lead to: If successful, this study could confirm that ABBV-951 effectively reduces 'off' time and improves daily function for people with advanced Parkinson's in routine care.
What could go wrong: This is an observational study, not a controlled trial, so results may be influenced by patient selection or other factors. Long-term benefits and risks are still being assessed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE (PD)

Contacts and locations

Locations

Atrium Health Wake Forest Baptist Medical Center /ID# 259387

Winston-Salem, North Carolina, 27157, United States
Banner Sun Health Research Institute /ID# 253461

Sun City, Arizona, 85351, United States
Bispebjerg Hospital /ID# 252032

Copenhagen, Capital Region, 2400, Denmark
Boston Medical Center Health System /ID# 269765

Brighton, Massachusetts, 02135, United States
CHUM - Centre hospitalier de l'Universite de Montréal /ID# 269689

Montreal, Quebec, H2X 0A9, Canada
Centre de Recherche St-Louis /ID# 262746

Québec, Quebec, G1W 4R4, Canada
Centrum for neurologi /ID# 252118

Stockholm, Stockholm County, 113 65, Sweden
Cleveland Clinic Lou Ruvo Cent /ID# 259390

Las Vegas, Nevada, 89106-0100, United States
Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 261402

Santiago de Compostela, A Coruna, 15706, Spain
David L. Kreitzman, MD, PC /ID# 259397

Commack, New York, 11725-6021, United States
Evergreenhealth Medical Center /ID# 268120

Kirkland, Washington, 98034, United States
Georgetown University Hospital /ID# 259381

Washington D.C., District of Columbia, 20007, United States
Hadassah Medical Center-Hebrew University /ID# 257717

Jerusalem, 91120, Israel
Hospital Clinico San Carlos /ID# 260922

Madrid, 28040, Spain
Hospital General Universitario de Elche /ID# 254438

Elche, Alicante, 03203, Spain
Hospital Universitario Puerta de Hierro - Majadahonda /ID# 260921

Majadahonda, Madrid, 28222, Spain
Hospital Universitario Virgen de las Nieves /ID# 257588

Granada, 18014, Spain
Hospital Universitario Virgen del Rocio /ID# 254437

Seville, 41013, Spain
Inland Northwest Research /ID# 253460

Spokane, Washington, 99202-1342, United States
Kansas City VA Medical Center /ID# 253466

Kansas City, Missouri, 64128, United States
Kepler Universitaetsklinikum GmbH /ID# 262776

Linz, Upper Austria, 4020, Austria
Klinik Ottakring /ID# 262773

Vienna, State of Vienna, 1160, Austria
Kliniken Beelitz GmbH /ID# 252665

Beelitz-Heilstätten, 14547, Germany
Klinikum Ernst von Bergmann /ID# 252375

Potsdam, Brandenburg, 14467, Germany
Klinikum Osnabrueck GmbH /ID# 252275

Osnabrück, Lower Saxony, 49076, Germany
Klinikum der Universitaet Muenchen Grosshadern /ID# 255574

Munich, Bavaria, 81337, Germany
Knappschaftskrankenhaus Bottrop /ID# 252274

Bottrop, 46242, Germany
Krankenhaus Martha-Maria Halle-Doelau /ID# 260372

Halle, Saxony-Anhalt, 06120, Germany
Medizinische Universitaet Graz /ID# 262774

Graz, Styria, 8010, Austria
Medizinische Universitaet Innsbruck /ID# 262775

Innsbruck, Tyrol, 6020, Austria
N1 Research, LLC /ID# 264221

Orlando, Florida, 32825-3769, United States
NeuroCare Center /ID# 259392

Canton, Ohio, 44718-2531, United States
Northwell Health /ID# 253469

Lake Success, New York, 11042, United States
Northwestern Medicine Primary And Specialty Care Lavin Family Pavilion /ID# 266977

Chicago, Illinois, 60611, United States
Novant Health Neurology and Sleep /ID# 259391

Charlotte, North Carolina, 28207-1100, United States
Ochsner Medical Center - Jefferson Highway /ID# 269764

New Orleans, Louisiana, 70121, United States
Odense University Hospital /ID# 252036

Odense, Region Syddanmark, 5000, Denmark
Parkinson's Disease and Movement Disorders Center of Boca Raton /ID# 253465

Boca Raton, Florida, 33486, United States
Parkinson's Research Centers of America - Palo Alto /ID# 264703

Palo Alto, California, 94301-2011, United States
Parkinson-Klinik Ortenau GmbH&Co KG /ID# 252376

Wolfach, Baden-Wurttemberg, 77709, Germany
Rabin Medical Center. /ID# 257716

Petah Tikva, 4941492, Israel
Rambam Health Care Campus- Haifa /ID# 260421

Haifa, 3525408, Israel
Rigshospitalet Glostrup /ID# 252035

Glostrup Municipality, Capital Region, 2600, Denmark
Sahlgrenska Universitetssjukhuset /ID# 252115

Gothenburg, Västra Götaland County, 413 46, Sweden
Shaare Zedek Medical Center /ID# 257715

Jerusalem, Jerusalem, 91031, Israel
Spitalul Clinic Colentina /ID# 252250

Bucharest, 020121, Romania
Spitalul Clinic Judetean de Urgenta Brasov /ID# 253308

Brasov, 500326, Romania
Spitalul Clinic Judetean de Urgenta Constanta /ID# 252251

Constanța, 900591, Romania
Spitalul Clinic Judetean de Urgenta Targu Mures /ID# 252247

Târgu Mureş, 540136, Romania
Spitalul Clinic Judetean de Urgenta Timisoara /Id# 252248

Timișoara, Timiș County, 300736, Romania
Spitalul Clinic Judetean de Urgenta Timisoara /Id# 252249

Timișoara, Timiș County, 300736, Romania
Tel Aviv Sourasky Medical Center /ID# 254824

Tel Aviv, Tel Aviv, 6423906, Israel
Texas Movement Disorder Specialists /ID# 253473

Georgetown, Texas, 78628-4126, United States
The Chaim Sheba Medical Center /ID# 254823

Ramat Gan, Tel Aviv, 5265601, Israel
The Movement Disorder Clinic of Oklahoma /ID# 253463

Tulsa, Oklahoma, 74136-6378, United States
The Ottawa Hospital - General Campus /ID# 263315

Ottawa, Ontario, K1H 8L6, Canada
The Royal Melbourne Hospital /ID# 259671

Parkville, Victoria, 3050, Australia
Univ Texas HSC San Antonio /ID# 259394

San Antonio, Texas, 78229-3901, United States
University of Alabama at Birmingham - Main /ID# 253477

Birmingham, Alabama, 35233, United States
University of Calgary /ID# 262833

Calgary, Alberta, T2N 4Z6, Canada
University of Florida College of Medicine /ID# 259383

Gainesville, Florida, 32610, United States
University of Miami /ID# 259396

Miami, Florida, 33138, United States
University of Minnesota - Minneapolis /ID# 268121

Minneapolis, Minnesota, 55455-0341, United States
University of South Florida- Neuroscience Institute /ID# 253470

Tampa, Florida, 33613, United States
University of Utah /ID# 253471

Salt Lake City, Utah, 84112-5500, United States
Uppsala University Hospital /ID# 252119

Uppsala, Uppsala County, 75185, Sweden
Vanderbilt University Medical Center /ID# 253474

Nashville, Tennessee, 37232-0011, United States
Westmead Hospital /ID# 259670

Westmead, New South Wales, 2145, Australia

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