New shorter chemo combo shows promise for hodgkin lymphoma

NCT ID NCT07002216

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing a shortened course of a drug combination called BrECADD for people with advanced Hodgkin lymphoma. The goal is to see if a shorter treatment can still control the cancer while reducing side effects. About 48 adults aged 18 to 60 will receive up to four cycles of the therapy. The study also looks at a blood test to track how well the treatment is working.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Brentuximab vedotin, etoposide, cyclophosphamide, doxorubicin, dacarbazine, and dexamethasone (BrECADD)

What this could lead to

If successful, this could offer a shorter, more tolerable chemotherapy regimen for advanced Hodgkin lymphoma, potentially reducing side effects while maintaining effectiveness.

What could go wrong

This is a small, early-phase trial with only 48 participants, so results may not apply to all patients. The drug combination still carries significant side effects, and it is not yet known if it works better than standard treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

classic Hodgkin lymphoma Hodgkins lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33146, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact