New shorter chemo combo shows promise for hodgkin lymphoma

NCT ID NCT07002216

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial is testing a shortened course of a drug combination called BrECADD for people with advanced Hodgkin lymphoma. The goal is to see if a shorter treatment can still control the cancer while reducing side effects. About 48 adults aged 18 to 60 will receive up to four cycles of the therapy. The study also looks at a blood test to track how well the treatment is working.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Brentuximab vedotin, etoposide, cyclophosphamide, doxorubicin, dacarbazine, and dexamethasone (BrECADD)
What this could lead to
If successful, this could offer a shorter, more tolerable chemotherapy regimen for advanced Hodgkin lymphoma, potentially reducing side effects while maintaining effectiveness.
What could go wrong
This is a small, early-phase trial with only 48 participants, so results may not apply to all patients. The drug combination still carries significant side effects, and it is not yet known if it works better than standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33146, United States

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