New scan spots hidden thyroid tumors that resist standard treatment

NCT ID NCT04927416

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special PET scan using a radioactive tracer called 68Gallium-DOTATATE can better detect thyroid cancer that has spread and no longer responds to standard radioactive iodine therapy. About 54 adults with metastatic thyroid cancer will receive one injection of the tracer and undergo a PET/CT scan. The goal is to see how many participants have tumors that light up on the scan, which could guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

68Gallium-DOTATATE (a radioactive tracer for PET/CT scans)

What this could lead to

If successful, this imaging method could help doctors identify which thyroid cancer patients might benefit from treatments targeting a specific tumor marker (SSTR2).

What could go wrong

This is a small, early-phase imaging study, not a treatment trial. It may not lead to direct patient benefits, and the tracer's ability to improve outcomes is unproven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

differentiated thyroid carcinoma medullary thyroid gland carcinoma metastatic malignant neoplasm Neoplasm Metastasis thyroid cancer thyroid Hurthle cell carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••