New PET scans could unmask hidden tumors in rare hormone disorder

NCT ID NCT02019706

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares advanced PET scans (68Ga-DOTATATE and F-DOPA) with standard imaging to locate hidden tumors causing ectopic Cushing syndrome. About 80 adults with this condition will undergo multiple scans over time. The goal is to see which scan or combination best finds the tumor source, potentially improving diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

68Ga-DOTATATE and 18F-DOPA radioligands

What this could lead to

If successful, this could help doctors find hidden tumors in people with ectopic Cushing syndrome, leading to more targeted treatment.

What could go wrong

This is a Phase 2 study with only 80 participants, so results may not apply to everyone. The imaging techniques may not find all tumors, and radiation exposure is a minor risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cushing syndrome ectopic Cushing syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States