New imaging tracer could sharpen detection of aggressive breast cancer

NCT ID NCT01093612

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a special PET scan using a radioactive tracer called 64Cu-DOTA-trastuzumab in 18 women with advanced HER2-positive breast cancer. The goal is to see if this scan can better identify HER2-positive tumors compared to standard imaging. If it works, it may help doctors choose more targeted treatments for each patient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

copper Cu 64-DOTA-trastuzumab (a radioactive tracer for PET scans)

What this could lead to

If successful, this imaging method could help doctors more accurately identify HER2-positive tumors and plan better treatments for advanced breast cancer.

What could go wrong

This is a very small pilot study with only 18 participants, so results may not apply to all patients. The technique is still experimental and not yet proven to improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States