New drug helps surgeons see brain tumors in kids – but is it safe?

NCT ID NCT04738162

First seen Jan 09, 2026 · Last updated May 01, 2026 · Updated 14 times

Summary

This study looked at whether a drug called 5-ALA is safe for children and teenagers with brain tumors. The drug makes tumor cells glow during surgery, helping surgeons remove more of the tumor. The study included 78 children aged 3 to 18 and focused on tracking any serious side effects. The goal was to see if this technique can be used safely in younger patients.

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Contacts and locations

Locations

  • Neurochirurgische Klinik der Universität München (LMU)

    München, 81377, Germany

  • Prinses Máxima Centrum voor kinderoncologie BV

    Utrecht, 3584, Netherlands

  • University Hospital Münster, Klinik für Neurochirurgie

    Münster, 48149, Germany

  • Universitätsklinikum Augsburg, Klinik für Neurochirurgie

    Augsburg, 86146, Germany

  • Universitätsklinikum Essen, Klinik für Neurochirurgie

    Essen, 45147, Germany

  • Universitätsklinikum Tübingen, Klinik für Neurochirurgie

    Tübingen, 72076, Germany

  • Universitätsmedizin Mainz, Klinik und Poliklinik für Neurochirurgie

    Mainz, 55131, Germany

Conditions

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