3D tumor maps could sharpen radiation targeting in head and neck cancer

NCT ID NCT05743569

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether creating a virtual 3D map of a patient's removed tumor helps doctors plan radiation therapy more precisely. Researchers will compare standard radiation plans with plans that include the 3D map to see if it changes the treatment area or reduces radiation to nearby healthy organs. The study involves 13 adults with head and neck cancer who have had surgery. All patients will still receive standard radiation treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
virtual 3D specimen mapping tool
What this could lead to
If successful, this could lead to more precise radiation planning, potentially reducing side effects by better targeting tumors and sparing healthy tissue.
What could go wrong
This is a very small, early feasibility study (13 participants) that only compares two plans on paper—patients still receive standard care. The tool may not improve outcomes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt Medical Center

    Nashville, Tennessee, 37232, United States

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