New imaging agent could reveal prostate cancer treatment success in real time

NCT ID NCT05155046

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing whether a special PET scan tracer called 18F-DCFPyL can accurately show how prostate cancer responds to standard radiation therapy. About 130 adults with newly diagnosed, localized prostate cancer will receive the tracer and undergo PET/CT scans at several points during treatment. The goal is to see if this imaging method can distinguish between cancer that is responding locally and cancer that has spread, which could help doctors personalize care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-DCFPyL (a radioactive tracer used in PET scans)

What this could lead to

If successful, this imaging method could help doctors quickly see if prostate cancer treatment is working, potentially allowing for earlier adjustments to therapy.

What could go wrong

This is a phase 2 trial with only 130 participants, so results may not apply to everyone. The imaging agent is used for diagnosis, not treatment, so it won't directly improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••