New imaging agent could reveal prostate cancer treatment success in real time
NCT ID NCT05155046
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 4 times
Summary
This phase 2 trial is testing whether a special PET scan tracer called 18F-DCFPyL can accurately show how prostate cancer responds to standard radiation therapy. About 130 adults with newly diagnosed, localized prostate cancer will receive the tracer and undergo PET/CT scans at several points during treatment. The goal is to see if this imaging method can distinguish between cancer that is responding locally and cancer that has spread, which could help doctors personalize care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 18F-DCFPyL (a radioactive tracer used in PET scans)
- What this could lead to
- If successful, this imaging method could help doctors quickly see if prostate cancer treatment is working, potentially allowing for earlier adjustments to therapy.
- What could go wrong
- This is a phase 2 trial with only 130 participants, so results may not apply to everyone. The imaging agent is used for diagnosis, not treatment, so it won't directly improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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Other studies related to the condition(s) this trial covers.
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