University Of Southampton
Clinical trials sponsored by University Of Southampton, explained in plain language.
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New combo shows promise for tough esophageal cancer
Disease control CompletedThis study tested a two-step treatment for people with advanced esophageal or stomach cancer that has a specific genetic marker (MGMT deficiency). First, patients took a chemotherapy-like drug (temozolomide) to prime the tumor, then received an immunotherapy drug (nivolumab). The…
Phase: PHASE2 • Sponsor: University of Southampton • Aim: Disease control
Last updated Jun 12, 2026 12:05 UTC
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New automatic device could speed up leg ulcer care
Diagnosis CompletedThis study compared an automatic device (MESI MD ABPI) with a manual device (Huntleigh Dopplex) for measuring blood pressure in the ankles of people with leg ulcers. The goal was to see if the automatic device gives similar results and can help nurses decide on the right treatmen…
Sponsor: University of Southampton • Aim: Diagnosis
Last updated Jun 01, 2026 18:02 UTC
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Broken bones, broken spirits: new study tracks mental health after falls
Knowledge-focused CompletedThis study looked at how often older adults feel anxious or depressed after breaking a bone and having surgery. Researchers used a simple questionnaire to measure these feelings in 40 patients during their hospital stay and one month later. The goal was to understand how common t…
Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:24 UTC
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Snap and track: new plate camera could revolutionize hospital diets
Knowledge-focused CompletedThis study tested a simple plate imaging system to measure how much food stroke patients eat in the hospital. About 50 patients took part over 12 weeks. The goal was to see if this camera-based method works well for tracking nutrition in a real hospital ward.
Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:10 UTC
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Cutting meds, not care: new approach tested in seniors
Knowledge-focused CompletedThis study tested whether a team-based plan to reduce anticholinergic medications (drugs that can cause confusion and falls) is practical and acceptable for hospitalized patients aged 65 and older. Twenty-one participants were enrolled, and researchers measured changes in medicat…
Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:06 UTC