University Of East Anglia

This trial tests whether empagliflozin, a drug already used for diabetes and heart failure, can prevent the heart muscle from thickening or developing fibrosis in people with moderate aortic stenosis. Participants will receive either empagliflozin or standard care for six months,…

This study tested a 22-minute online training program for parents of children aged 5-12 with long-term health conditions. The training taught simple skills based on Acceptance and Commitment Therapy (ACT) to help parents support their child's anxiety. Only 17 parents took part, a…

This study tested a 'wisdom enhancement' technique added to standard therapy for depression after a stroke. Three stroke survivors tracked their mood, identity, self-esteem, and wisdom daily. The goal was to see if this approach could improve emotional well-being, but the very sm…

This pilot study tested whether an adapted version of cognitive stimulation therapy (CST) is acceptable and feasible for stroke survivors who are pre-frail. Ten stroke survivors and their carers took part in focus groups to share their experiences. The goal was to see if CST coul…

This completed study from the University of East Anglia looked at how gut bacteria break down certain plant compounds (flavan-3-ols) in people with different versions of the APOE gene, which is linked to Alzheimer's risk. 49 healthy adults donated stool and saliva samples. The go…