University Hospitals Cleveland Medical Center

This study tests a drug called deutetrabenazine for tardive dyskinesia (uncontrollable movements) in 25 adults with intellectual/developmental disabilities and psychiatric or behavioral disorders. Participants will take the medication for 24 weeks to see if it reduces movement pr…

This trial tests a surgery that uses a piece of the patient's own abdominal muscle to wrap around the bladder, helping it squeeze and empty. The study will include 50 people with long-term urinary retention who have not gotten better with other treatments. Researchers will measur…

This study explores whether artificial intelligence can help emergency department doctors identify depression and anxiety in patients. Researchers will record 30 adult patients' facial expressions and voice tones as they read a story, and then use AI to analyze those recordings. …

This study tests whether adding Osteopathic Manipulative Treatment (OMT) — a non-invasive, hands-on therapy — to standard care helps people with frozen shoulder recover faster and feel more satisfied. About 300 adults who have not yet been treated for frozen shoulder will be assi…

This study tests whether a lecture on good posture, a quick pre-surgery time-out, and short stretch breaks during operations can reduce pain and injuries in OBGYN surgeons. Fifty surgeons (attendings, residents, and fellows) at one hospital will report their pain levels before an…

This early-stage trial will test whether higher-than-standard doses of memantine, a drug already approved for Alzheimer's, are safe and tolerable in 25 adolescents and young adults with Down syndrome. The study also looks for early signs that the drug might improve memory and thi…