University Hospital Of Cologne

This study tests whether rapidly switching from a standard heart pump (Impella CP) to a more powerful one (Impella 5.5) within 24 hours after a heart attack improves outcomes for people in cardiogenic shock. About 115 adults aged 18-77 with severe shock will be enrolled. The goal…

This study tests a combination of two types of radiation therapy for elderly or frail patients with rectal cancer who cannot or will not have surgery. The goal is to shrink or control the tumor while maintaining quality of life. Researchers will follow 80 participants for up to t…

This registry follows 1,000 adults with mitral regurgitation who receive the MitraClip G5, a device that repairs the heart valve without open-heart surgery. Researchers will measure how well the procedure reduces valve leakage and improves symptoms like shortness of breath. All d…

This study tests whether a 4-week program of high-intensity interval training, specialized nutrition, and psychological support before major gastrointestinal cancer surgery can lower the risk of serious complications afterward. About 400 high-risk patients will be randomly assign…