University Hospital Of Cologne

This study tests a combination of external beam radiotherapy and internal high-dose-rate brachytherapy for elderly or frail patients with rectal cancer who cannot have or refuse surgery. The goal is to achieve a complete or near-complete response within 12 months and maintain it …

This study is a registry that will collect information from 1,000 patients with mitral regurgitation (a leaky heart valve) who receive a newer version of the MitraClip device, called G5. The MitraClip is a small clip placed via a tube in a leg vein to repair the valve without ope…

This study tests whether a 4-week program of high-intensity interval training, specialized nutrition, and psychological support before major gastrointestinal cancer surgery can lower the risk of serious complications. 400 high-risk patients will be randomly assigned to either thi…