Transcend Therapeutics

This study followed 44 people with PTSD who had already completed a prior methylone (TSND-201) trial. Over 52 weeks, researchers checked their symptoms and safety each month. If PTSD symptoms returned, participants could receive more methylone treatment. The goal was to see if th…

This study tested whether methylone, a substance similar to MDMA, can safely reduce PTSD symptoms in adults. 79 participants with moderate to severe PTSD received either methylone or a placebo once a week for four weeks, then were followed for six more weeks. The goal was to see …

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

This early-stage trial tested the safety and drug levels of methylone in 40 healthy volunteers aged 25 to 55. Participants received a single oral dose of methylone or a placebo. The study measured how the drug moves through the body and checked for side effects. This is a first s…