The University Of Queensland

This pilot study tests whether using a cap containing chlorhexidine on dialysis catheters can reduce infections compared to standard caps. Sixty adults with kidney failure who need dialysis through a central line will be randomly assigned to one of the two caps. The main goal is …

This trial tests a new combination of antibiotics (called Arm D) against standard treatments for a rare lung infection caused by Mycobacterium abscessus. About 300 people with or without cystic fibrosis will take part. The goal is to see if the new combo clears the infection bett…

This study will test different methods to prevent infections and other problems from central lines (tubes placed in large veins) in 2,500 patients. It compares special antimicrobial caps and a skin anchor device against standard care. The goal is to find the best ways to keep pat…

This study will test whether a special type of heart ultrasound can better predict serious outcomes in adults with sepsis in the ICU. Researchers will compare these new measurements with standard ones in 200 patients across four countries. Participants will have regular echocardi…

This study looks at whether adding a special brain-wave display (called density spectral array, or DSA) to the standard monitor (bispectral index, or BIS) helps doctors better detect when older adults (65+) wake up from anesthesia. The goal is to reduce the risk of being aware du…