The Third Xiangya Hospital Of Central South University

This Phase 2 trial tests whether adding two drugs (benmelstobart and anlotinib) to standard chemotherapy before chemoradiation helps people with stage III lung cancer that cannot be removed by surgery. 152 participants will be randomly assigned to receive either the new induction…

This study compares two glucose monitoring methods—continuous glucose monitors (CGM) and traditional finger-prick tests—in adults with type 2 diabetes who are taking the drug dapagliflozin. The 120 participants will be split into two groups and followed for 12 weeks to see which …

This study tests an oral traditional Chinese medicine made from the fungus C. cicadae in people with ALS who have high levels of certain fats (sphingolipids) in their blood. About 84 participants will receive either the medicine or a placebo for 6 months, with follow-up for 9 mon…

This study tests whether choosing blood pressure medication based on a person's specific heart and blood vessel measurements (hemodynamic phenotyping) works better than the usual guideline-based approach. About 240 adults with mild-to-moderate hypertension who have never taken bl…

This early-phase trial will test a new tumor vaccine (SapDM275) combined with standard chemotherapy in 13 people with metastatic pancreatic cancer who have not had prior treatment. The vaccine aims to help the immune system attack cancer cells. The main goal is to check safety, b…