New drug cocktail aims to boost lung cancer treatment before radiation
NCT ID NCT07643350
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether adding two drugs (benmelstobart and anlotinib) to standard chemotherapy before chemoradiation helps people with stage III lung cancer that cannot be removed by surgery. 152 participants will be randomly assigned to receive either the new induction therapy followed by chemoradiation and maintenance immunotherapy, or chemoradiation followed by maintenance immunotherapy alone. The study will track how long the cancer stays under control and look for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Benmelstobart (an immunotherapy drug) and anlotinib (a targeted therapy drug), plus chemotherapy
- What this could lead to
- If successful, this approach could improve how long people with advanced lung cancer live without their disease getting worse, and may point to a more effective treatment plan.
- What could go wrong
- This is an early Phase 2 trial with only 152 people, so results are not definitive. Adding more drugs before radiation may increase side effects without clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
ThirdXiangyaHCSU
Changsha, Hunan, China
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