Swog Cancer Research Network
Clinical trials sponsored by Swog Cancer Research Network, explained in plain language.
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New drug duo battle for lung cancer survival
Disease control OngoingThis study is for people with advanced or recurrent non-small cell lung cancer that has a specific genetic change (EGFR mutation). It compares two treatment approaches: taking a pill called afatinib alone, or taking afatinib plus receiving an IV drug called cetuximab. The main go…
Phase: PHASE2, PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Apr 01, 2026 23:11 UTC
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New hope for tough leukemia: trial tests powerful drug combo
Disease control ENROLLING_BY_INVITATIONThis study is testing if adding a new drug, asciminib, to a standard treatment regimen works better for adults newly diagnosed with a specific, aggressive form of leukemia called Philadelphia chromosome-positive ALL. The goal is to see if this combination can drive the cancer int…
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Major trial tests personalized drug combo to keep blood cancer at bay
Disease control OngoingThis study is for people with multiple myeloma who have had a stem cell transplant. It tests whether adding a drug called daratumumab to the standard maintenance drug lenalidomide is better at keeping the cancer from coming back. A key part of the study uses a very sensitive bloo…
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New pill targets genetic driver in advanced lung cancer
Disease control OngoingThis study is testing an oral drug called selpercatinib for people with advanced non-small cell lung cancer that has a specific genetic change called a RET fusion. The goal is to see how well the drug shrinks tumors and controls the cancer by blocking the abnormal protein driving…
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Major trial tests new drug combo to stop aggressive breast Cancer's return
Disease control OngoingThis large study tested whether adding a drug called everolimus to standard hormone therapy is better at preventing breast cancer from coming back. It involved nearly 2,000 patients with a high-risk type of breast cancer that is fueled by hormones. The goal was to see if the one-…
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New pill targets 'Undruggable' cancer mutation in advanced lung cancer
Disease control OngoingThis study is testing an experimental pill called AMG 510 for people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. The pill is designed to block this specific mutation, which can drive cancer growth, in patients whose cancer has wor…
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 10, 2026 12:52 UTC
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New drug duo aims to wipe out more leukemia cells
Disease control OngoingThis study is testing if adding a drug called ruxolitinib to standard CML medications helps patients achieve a deeper level of remission. It involves adults with chronic phase CML who still have a small amount of detectable disease despite being on treatment. Participants are ran…
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 02, 2026 15:22 UTC
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New web tools aim to guide women through tough breast cancer prevention decisions
Prevention OngoingThis study tests whether web-based decision support tools help women at high risk for breast cancer make more informed choices about preventive medications. It involves 412 women with specific high-risk breast conditions who are considering drugs that can lower their cancer risk.…
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Cancer's hidden cost: new program aims to ease financial pain for patients
Symptom relief OngoingThis study tests whether a financial counseling program can reduce money problems and stress for people with cancer and their partners. It compares two groups: one gets basic financial education, and the other gets that plus monthly meetings with a financial counselor. The goal i…
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated Apr 01, 2026 23:11 UTC
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Can we predict who gets nerve damage from chemo?
Knowledge-focused OngoingThis study aims to create a tool to predict which cancer patients are most likely to develop nerve damage (like tingling or numbness in hands and feet) from a common class of chemotherapy drugs called taxanes. Researchers will follow over 1,300 patients with breast, lung, or ovar…
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Cancer experts team up to crack genetic code for better treatments
Knowledge-focused OngoingThis study is testing whether having a team of cancer genetics experts review a patient's tumor test results helps doctors choose more effective treatments. It compares the usual approach where doctors review results alone against having a special 'genomic tumor board' provide ex…
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Simple blood test could give early warning for Cancer's return
Knowledge-focused OngoingThis study is testing whether a specific substance in the blood (called miRNA 371) can help doctors predict if testicular cancer will return after initial treatment. Researchers are following 956 newly diagnosed patients for up to 3 years, collecting blood samples every few month…
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC