Sun Yat-sen Memorial Hospital Of Sun Yat-sen University

This study tests whether adding the drug QL1706 to standard chemotherapy before a hysterectomy can improve outcomes for people with locally advanced cervical cancer. About 54 participants will receive the combination every three weeks for three cycles, then undergo surgery if the…

This early-phase study tests whether adding the blood-pressure drug propranolol to standard immunotherapy and chemotherapy before surgery can help treat bladder cancer that has spread to lymph nodes. About 12 adults with this condition will receive the combination and be monitore…

This study tests whether adding a new immunotherapy drug (cadonilimab) to chemotherapy before standard radiation can shrink tumors better in people with locally advanced cervical cancer. The trial involves 29 participants and aims to see how many respond to the treatment. Researc…

This study tests whether adding the drug pyrotinib to standard chemotherapy before surgery can improve outcomes for women with stage II to III hormone receptor-positive, HER2-negative breast cancer that also has high levels of the HER4 protein. About 140 participants will receive…

This study tests whether giving two drugs (trastuzumab and a taxane) before surgery can shrink HER2-positive breast carcinoma in situ tumors enough to allow breast-conserving surgery instead of mastectomy. About 54 women aged 18-70 with tumors at least 2 cm will receive 4-6 cycle…

This study tests whether a combination of two targeted pills (fluorizoparib and apatinib) works better than standard chemotherapy for people with a specific genetic type of advanced breast cancer (HRD-positive, HER2-negative). About 200 participants will be randomly assigned to e…

This study tests whether giving a combination of the immunotherapy drug tirellizumab and chemotherapy before surgery can improve outcomes for people with early-stage oral cancer. About 60 participants will be randomly assigned to either the new drug combo plus surgery or standard…

This study tests whether adding the targeted drug pyrotinib to standard chemotherapy can better shrink tumors before surgery in people with a common type of early breast cancer (HR-positive, HER2-low). About 160 adults with high-risk, early-stage breast cancer will be randomly as…

This phase 3 trial tests whether mecobalamin (a form of vitamin B12) can prevent severe hand-foot syndrome in early breast cancer patients taking capecitabine. About 234 women will receive either mecobalamin or a placebo. The goal is to see if the vitamin reduces painful skin rea…

This study tests whether an AI system can create safe and effective exercise plans for women recovering from breast cancer surgery. Researchers will compare the AI's plans to those made by doctors. The goal is to make rehabilitation more personalized and accessible.

This study looks at whether a personalized blood test can detect the return of early-stage non-small cell lung cancer before standard imaging like CT scans. Researchers will follow 450 patients after surgery, using a custom test based on each person's tumor DNA. The goal is to se…

This study checks if two new methods (M-Score and BISSI) are reliable and accurate for measuring symptom severity in women with non-lactational mastitis (breast inflammation not related to breastfeeding). Researchers will enroll 320 women aged 18-65 with confirmed non-lactational…