Springworks Therapeutics, Inc., A Healthcare Company Of Merck Kgaa, Darmstadt, Germany

This study looked at how a drug called nirogacestat changes the way the body processes five other common drugs in 20 healthy men. Participants took the other drugs alone and then again with nirogacestat to measure differences. The goal was to understand potential drug interaction…

This study looked at how two common stomach acid medications (famotidine and rabeprazole) affect the levels of the drug nirogacestat in the blood. Twenty-four healthy adult men took nirogacestat alone and with each acid reducer. The goal was to see if these stomach drugs change h…

This study looked at how carbamazepine, a drug used for seizures, changes the amount of mirdametinib in the blood. Thirty-six healthy adults took both drugs by mouth, and researchers measured drug levels over time. The goal was to understand if carbamazepine speeds up the breakdo…