Acid reducers may change how drug works in body

NCT ID NCT07171619

First seen Sep 30, 2025 · Last updated May 14, 2026 · Updated 30 times

Summary

This study looked at how two common stomach acid medications (famotidine and rabeprazole) affect the levels of the drug nirogacestat in the blood. Twenty-four healthy adult men took nirogacestat alone and with each acid reducer. The goal was to see if these stomach drugs change how much nirogacestat gets absorbed, which helps doctors decide the best way to take the medicine.

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Contacts and locations

Locations

  • Medpace

    Cincinnati, Ohio, 45227, United States

Conditions

Explore the condition pages connected to this study.