Ruijin Hospital

This early-phase study tests a personalized mRNA vaccine (XP-004) combined with a PD-1 inhibitor in 20 patients who had pancreatic cancer surgery but cannot take chemotherapy. The vaccine is designed to train the immune system to attack cancer cells based on each patient's unique…

This study tests a combination of three drugs (orelabrutinib, lisaftoclax, and rituximab) in people with a fast-growing type of lymphoma called mantle cell lymphoma that hasn't been treated yet. The goal is to see how well the drugs shrink tumors and how safe they are. About 25 a…

This study looks at whether a donor stem cell transplant (allogeneic) can help prevent leukemia from coming back in people newly diagnosed with a high-risk form of acute myeloid leukemia (CBF-AML). About 90 participants will receive standard chemotherapy followed by a transplant.…

This study explores whether a new type of PET scan can help doctors see how ANCA-associated vasculitis affects the lungs and kidneys. The researchers will use a special tracer that targets certain cells involved in tissue scarring. By scanning the whole body at once, they hope to…

This study looks at whether analyzing how people with dystonia walk before deep brain stimulation (DBS) surgery can help predict how well the surgery will work. About 50 adults scheduled for DBS will wear small sensors while walking. Researchers will then compare their walking pa…