Royal Brompton & Harefield Nhs Foundation Trust

This study compares two steroid-tapering schedules for people with stable sarcoidosis who have been on prednisolone for at least six months. The goal is to see which approach helps more patients cut their dose by at least half without causing a flare-up. Researchers will also mon…

This study evaluates the Breathing Pattern Assessment Tool (BPAT), a checklist used by physiotherapists to diagnose breathing pattern disorder—a condition where breathing is inefficient, causing breathlessness. Researchers will compare BPAT scores with patient questionnaires and …

This study tests whether a wearable device called SleepImage can accurately detect respiratory failure in people with ALS (Lou Gehrig's disease). Researchers will compare the device's readings with standard overnight sleep tests in 15 patients. The goal is to find a simpler way t…

This study looks at how to best strengthen the diaphragm—the main breathing muscle—in patients who are on a ventilator and have a tracheostomy. Researchers will test four different levels of breathing resistance and ask patients how they feel during each one. The goal is to desig…

This pilot study looks at how anti-fibrotic medications affect body composition in people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). Researchers will use bioelectrical impedance analysis (BIA) and muscle ultrasound to track changes in muscle…

This study follows 60 women with cystic fibrosis (CF) who are planning a pregnancy, pregnant, or new parents, along with their babies. Researchers will track lung function, nutrition, mental health, and pregnancy outcomes, as well as infant health issues like liver function and l…