Royal Brompton & Harefield Nhs Foundation Trust

This study aims to see if a device called SleepImage can accurately detect respiratory failure in people with ALS (amyotrophic lateral sclerosis). Researchers will compare SleepImage data with standard overnight sleep tests in 15 adults with ALS. The goal is to find a simpler way…

This study looks at two different schedules for lowering steroid doses in people with stable sarcoidosis. The goal is to reduce long-term side effects like diabetes and bone loss while keeping the disease under control. About 100 adults on a stable low dose of prednisolone will b…

This study looks at how anti-fibrotic medications affect body composition in people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). Researchers will use bioelectrical impedance analysis (BIA) and muscle ultrasound to measure muscle and fat change…

This study follows 60 women with cystic fibrosis (CF) who are planning a pregnancy, are pregnant, or have recently given birth. Researchers will track their lung function, nutrition, and mental health, and also check the health of their babies, including liver function and lung d…

This study aims to find the right level of breathing exercise to strengthen the diaphragm in patients who have trouble coming off a ventilator. Researchers will test four different exercise levels on 40 adults with a tracheostomy, measuring muscle effort and asking patients how t…

This study looks at a tool called the Breathing Pattern Assessment Tool (BPAT) used by physiotherapists to check for breathing pattern disorder (BPD), a condition where breathing doesn't match the body's needs, causing breathlessness. Researchers will test if the BPAT is reliable…