Puretech

This early-stage study tested a new drug called LYT-200 in 101 adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had come back or stopped responding to treatment. The main goals were to check the drug's safety and find the right dose. While not…

This study tested a new drug called Lyt-100 (deupirfenidone) in 116 healthy adults aged 60-80 to see how safe it is and how the body processes it compared to the existing drug pirfenidone. The goal was to find the best dose for future studies, not to treat any disease. Participan…

This completed Phase 1 trial studied how deupirfenidone (LYT-100) and nintedanib interact in 24 healthy adults aged 18-65. Participants took both drugs over several weeks to measure drug levels and check for side effects. The goal was to understand potential drug-drug interaction…